Autoimmune diseases can be complex, unpredictable, and difficult to diagnose without specialised medical tests. Among these conditions, Systemic Lupus Erythematosus (SLE) is one of the most challenging disorders, often affecting the skin, kidneys, joints, and the immune system itself. One of the most reliable and widely used diagnostic tools for SLE is the Anti-dsDNA test, performed with high accuracy at Alnoor Diagnostic Centre, one of Pakistan’s trusted names in diagnostic healthcare.
The anti-dsDNA test plays a critical role in detecting antibodies that attack the body’s own double-stranded DNA. These antibodies are highly specific to lupus, making this test important for both diagnosis and monitoring disease activity. At Alnoor Diagnostic Centre, the test is conducted using advanced immunological technology, ensuring precise results, quick reporting, and clinically reliable measurements.
Whether you are experiencing symptoms of lupus, need routine monitoring, or your doctor has suggested further autoimmune screening, the Anti-dsDNA test at Alnoor Diagnostic Centre offers dependable results you can trust. In this article, you’ll find complete details about the Anti-dsDNA test price, purpose, preparation, process, normal values, booking information, and more.
What is the Anti-dsDNA Test?
The Anti-dsDNA (Anti-double-stranded DNA) test detects the presence of autoantibodies that attack the body’s own DNA. These antibodies are a hallmark of Systemic Lupus Erythematosus (SLE) and are used not only for diagnosis but also for monitoring disease severity.
What the test measures
- Levels of double-stranded DNA antibodies in the blood
- Immune system overactivity
- Lupus-related inflammation and autoimmune response
Why doctors recommend it
Doctors usually advise the anti-dsDNA test when they suspect:
- Systemic Lupus Erythematosus (SLE)
- Flare-up of existing lupus
- Kidney inflammation related to lupus (Lupus Nephritis)
- Unexplained joint pain or fatigue
- Abnormal ANA test results
Common uses
- Diagnosing SLE when ANA is positive
- Determining disease activity levels
- Assessing risk of organ involvement
- Monitoring treatment response
Why is the Anti-dsDNA Test Important?
The anti-dsDNA test is important because it is highly specific to lupus, unlike many other autoimmune markers. Its presence strongly indicates that the immune system is mistakenly attacking healthy tissues.
This test helps identify:
- The presence of lupus
- The severity of the disease
- The likelihood of kidney damage
- Whether medications are effectively reducing inflammation
Since anti-dsDNA levels often rise during a flare-up and decrease when the disease becomes controlled, ongoing testing is frequently recommended. Early detection through this test allows doctors to begin treatment sooner, preventing complications.
When Should You Get an Anti-dsDNA Test?
Doctors typically suggest this test when a person experiences symptoms associated with lupus or autoimmune inflammation.
You should get an anti-dsDNA test if you have:
- Persistent joint pain
- Chronic fatigue
- Butterfly-shaped rash on the face
- Unexplained fever
- Skin sensitivity to sunlight
- Swelling in legs (possible kidney involvement)
- Positive ANA test
- Family history of autoimmune disease
Other situations include:
- Follow-up testing to check lupus activity
- Monitoring kidney function in lupus patients
- Before adjusting treatment, such as steroids or immunosuppressants
How to Prepare for the Anti-dsDNA Test?
Good news, the Anti-dsDNA test requires no fasting, and preparation is simple.
Preparation Guidelines
- No fasting required
- Continue your routine diet
- Drink water to stay hydrated
- Inform your doctor about:
- Steroid medications
- Immunosuppressants
- Recent infections (can affect results)
Important Note
Do not stop any medication without your doctor’s approval, even if you are going for this test.
How is the Anti-dsDNA Test Performed at Alnoor Diagnostic Centre?
At Alnoor Diagnostic Centre, the Anti-dsDNA test is conducted with precision using automated immunology analysers. The process is safe, quick, and handled by trained phlebotomists.
Step-by-Step Process
- Registration at the reception or online through All Lab Tests
- Blood sample collection from a vein in your arm
- Sample labelling and processing in a sterile environment
- Testing performed using the ELISA or CLIFT method
- Quality control to ensure accuracy
- Report generation within the lab’s standard turnaround time
Why Alnoor Diagnostic Centre?
- Advanced technology
- Experienced pathology staff
- Strict sterilisation procedures
- Accurate, clinically approved results
Anti-dsDNA Test Report & Normal Values
Anti-dsDNA report results are usually given in IU/mL. Here is the commonly used reference range:
| Anti-dsDNA (ELISA Method) | Normal Values |
| Negative | < 30 IU/mL |
| Borderline | 30-75 IU/mL |
| Positive | > 75 IU/mL |
How to interpret results
- Negative: Low likelihood of active lupus
- Borderline: May require repeat testing or further evaluation
- Positive: Strong indication of lupus or increased disease activity
Important
Only a qualified doctor or rheumatologist can accurately interpret your report and diagnose lupus.
Understanding Abnormal Anti-dsDNA Results
If your anti-dsDNA levels are elevated, it doesn’t automatically mean you have lupus—but it increases the possibility significantly.
Common causes of high anti-dsDNA levels
- Systemic Lupus Erythematosus (SLE)
- Lupus Nephritis (kidney involvement)
- Drug-induced lupus (rare)
- Autoimmune flare-up due to infection or stress
What high values may indicate
- Active inflammation in the body
- Possible organ involvement, especially the kidneys
- Need for treatment adjustments
- Increased lupus severity
Follow-up tests are often recommended:
- ANA profile
- CBC
- ESR / CRP
- Complement levels (C3, C4)
- Kidney function tests (Creatinine, eGFR, Urine protein)
How to Manage Autoimmune Health Naturally (Guidance)
Although medical treatment is necessary for lupus, certain lifestyle habits can help reduce inflammation and support overall well-being.
Helpful tips:
- Maintain a balanced anti-inflammatory diet
- Stay hydrated
- Reduce stress through breathing exercises or yoga
- Get adequate rest
- Limit sun exposure
- Avoid smoking
- Take medications on time
- Regular follow-up with your doctor
These steps support your health but do not replace medical treatment.
Anti-dsDNA Test Cost at Alnoor Diagnostic Centre
The anti-dsDNA test cost at Alnoor Diagnostic Centre is Rs. 5500. This price makes it accessible for patients who require frequent monitoring for lupus and other autoimmune disorders.
You can book the test online easily and visit your nearest Alnoor Diagnostic Centre branch for sample collection. The test fee includes accurate processing, expert handling, and timely report delivery.
Alnoor Diagnostic Centre Anti-dsDNA Price in Pakistan
The Alnoor Diagnostic Centre Anti-dsDNA Test Price in Pakistan is Rs. 5500. Alnoor is known for reliable autoimmune testing, and this cost remains competitive compared to other major diagnostic labs.
You can book the test anywhere in Pakistan through All Lab Tests, check the test charges, and easily find the nearest Alnoor branch. This ensures a smooth and convenient testing experience for patients nationwide.
Where to Book the Anti-dsDNA Test in Pakistan
If you’re searching for “Anti-dsDNA test near me”, you can now compare prices, view test charges, and select the most suitable diagnostic lab through All Lab Tests.
Through the platform, you can:
- Compare the anti-dsDNA test cost in Pakistan
- Check Alnoor Diagnostic Centre test charges 2026
- Read lab reviews and service details
- Book online in minutes
- Visit any branch for sample collection
Booking through All Lab Tests saves time and ensures that you get high-quality, trusted test results.
Book Your Anti-dsDNA Test at Alnoor Diagnostic Centre
Get reliable and accurate autoimmune testing from one of Pakistan’s most trusted laboratories. Book your Anti-dsDNA test at Alnoor Diagnostic Centre today through All Lab Tests and benefit from:
- Easy online booking
- Verified and trusted lab network
- Fast and accurate reports
- Affordable testing charges
- Professional sample collection
Whether you are monitoring lupus, investigating symptoms, or following your doctor’s recommendation, Alnoor Diagnostic Centre ensures clinical accuracy and dependable results every time.
