Autoimmune diseases are becoming increasingly common, and early diagnosis is essential for better treatment outcomes. One of the most accurate and widely recommended diagnostic tests for autoimmune disorders, especially Systemic Lupus Erythematosus (SLE) is the Anti-dsDNA Test. If your doctor has advised this test, choosing a trusted and reliable diagnostic facility is crucial. Ibn-e-Sina Clinical Laboratory is one of Pakistan’s leading diagnostic labs, known for its accuracy, modern technology, and expert pathology services.
The Anti-dsDNA Test at Ibn-e-Sina Clinical Laboratory helps detect antibodies that attack the body’s own DNA. These antibodies are strongly associated with lupus and other autoimmune inflammatory conditions. In this article, we explain the complete details of the test, preparation steps, report interpretation, normal values, booking method, and the Ibn-e-Sina Anti-dsDNA Test price, so you can make an informed decision.
What is the Anti-dsDNA Test?
The Anti-double-stranded DNA (Anti-dsDNA) test measures the presence of antibodies that mistakenly target and attach to the body’s own DNA. These antibodies are commonly found in patients with Systemic Lupus Erythematosus (SLE), an autoimmune condition in which the immune system becomes overactive and attacks healthy tissues.
Doctors often recommend the Anti-dsDNA test when they suspect:
- Systemic Lupus Erythematosus (SLE)
- Autoimmune inflammatory disorders
- Kidney involvement in autoimmune diseases
- Skin rashes or joint inflammation with suspected autoimmune causes
- Persistent fatigue, fever, or unexplained body aches
- Positive ANA (Antinuclear Antibody) test requiring further confirmation
The Anti-dsDNA test plays a crucial diagnostic role because it is highly specific for lupus, making it more reliable than many other autoimmune tests.
Why is the Anti-dsDNA Test Important?
The importance of the anti-dsDNA test lies in its direct link with lupus. Unlike general autoimmune screening tests, Anti-dsDNA specifically identifies antibodies that attack DNA in the body’s cells.
Here’s why it matters:
1. Accurate Lupus Diagnosis
Anti-dsDNA antibodies are strongly associated with lupus. A high level often confirms the diagnosis when symptoms are present.
2. Helps Monitor Disease Severity
Doctors use this test to assess:
- Disease activity
- Risk of flare-ups
- Organ involvement (especially kidneys)
3. Predicts Kidney Damage (Lupus Nephritis)
High anti-dsDNA levels often indicate the possibility of kidney inflammation, allowing early treatment.
4. Helps Guide Treatment
Results help doctors decide:
- Medication adjustments
- Treatment duration
- Frequency of follow-up testing
This makes the Anti-dsDNA Test one of the most essential tests for anyone dealing with autoimmune symptoms.
When Should You Get an Anti-dsDNA Test?
A doctor may advise this test if you experience symptoms such as:
- Persistent joint pain or swelling
- Butterfly-shaped rash on the face
- Sensitivity to sunlight
- Unexplained fever or fatigue
- Hair loss or skin rashes
- Kidney problems (swelling, protein in urine)
- Chest pain or breathing difficulties
- Recurrent mouth sores
You may also need this test if:
- Your ANA test is positive
- You have a family history of autoimmune diseases
- Your doctor suspects lupus or related conditions
- You are already diagnosed with SLE and need regular monitoring
How to Prepare for the Anti-dsDNA Test?
The preparation for the anti-dsDNA test is simple and patient-friendly:
- No fasting required: You can eat and drink normally.
- Inform your doctor about medications, especially immunosuppressants or steroids.
- Avoid biotin supplements 24-48 hours before the test (if used).
- Stay hydrated for easier blood sample collection.
- Wear clothing that allows easy access to your arm for the blood draw.
Ibn-e-Sina Clinical Laboratory provides clear instructions and ensures a comfortable testing experience.
How is the Anti-dsDNA Test Performed at Ibn-e-Sina Clinical Laboratory?
The process is quick, safe, and handled by trained technicians.
Step-by-Step Testing Procedure
- Registration: You simply visit the nearest Ibn-e-Sina branch or book your Anti-dsDNA test online.
- Sample Collection: A small blood sample is collected from your vein (usually your arm).
- Laboratory Analysis: The sample is tested using advanced immunoassay systems that detect anti-dsDNA antibodies with high accuracy.
- Quality Control: Ibn-e-Sina follows strict internal standards and double-checks test results to ensure reliability.
- Report Delivery: Reports are usually available within 24-48 hours, both online and at the branch.
Ibn-e-Sina Clinical Laboratory is known for its high testing accuracy and professional handling, making it a trusted lab for autoimmune tests in Pakistan.
Anti-dsDNA Test Report & Normal Values
Below is a general reference range used for anti-dsDNA report antibody testing:
Anti-dsDNA Normal Values
| Result Range | Interpretation |
| < 25 IU/mL | Negative / Normal |
| 25 – 30 IU/mL | Borderline |
| > 30 IU/mL | Positive (Possible autoimmune activity) |
How to Interpret the Report
- Negative Result: No significant anti-dsDNA antibodies detected. Lupus is unlikely.
- Borderline Result: Further evaluation may be required.
- Positive Result: Suggests lupus or autoimmune activity. Doctors may conduct additional tests (ANA profile, ESR, CRP, kidney tests).
Important Note:
Only a qualified doctor or rheumatologist can diagnose lupus or interpret results fully.
Understanding Abnormal Results
If your anti-dsDNA levels are higher than normal, it may indicate:
1. Systemic Lupus Erythematosus (SLE)
This is the most common reason for elevated anti-dsDNA antibodies.
2. Lupus Nephritis
Abnormal results combined with kidney test abnormalities can indicate kidney inflammation.
3. Other Autoimmune Disorders
Although rare, mild elevations may also occur in:
- Sjögren’s syndrome
- Mixed connective tissue disease
- Rheumatoid arthritis (rarely)
4. Increased Disease Activity
If you already have lupus, rising anti-dsDNA levels may signal a flare-up.
Your doctor may advise additional tests such as:
- ANA
- ENA Profile
- CRP
- ESR
- Kidney Function Tests
- Urine protein tests
How to Improve Autoimmune Health Naturally
While medication is essential for autoimmune conditions, lifestyle changes can support better health.
1. Anti-Inflammatory Diet
Include:
- Fresh fruits
- Vegetables
- Omega-3 fatty acids
- Turmeric and ginger
Avoid:
- Processed foods
- Excess sugar
- Fried foods
2. Sun Protection
People with lupus are often sensitive to UV rays. Use sunscreen and avoid direct sunlight.
3. Stress Management
Stress can trigger autoimmune flare-ups. Try:
- Yoga
- Meditation
- Light exercise
4. Adequate Sleep
Aim for 7-9 hours of sleep daily to support immune balance.
5. Regular Monitoring
Getting your anti-dsDNA test regularly helps keep disease activity under control.
Anti-dsDNA Test Cost at Ibn-e-Sina Clinical Laboratory
The Anti-dsDNA Test cost at Ibn-e-Sina Clinical Laboratory is Rs. 3,500. This price makes it one of the most affordable autoimmune tests offered by a leading diagnostic lab in Pakistan. You can book the test online, visit your nearest branch, or avail home sample collection in selected areas.
The test fee may vary slightly by city or updated lab charges, but the average Ibn-e-Sina Anti-dsDNA price remains around Rs. 3,500.
Ibn-e-Sina Anti-dsDNA Test Price in Pakistan
Looking for the updated Ibn-e-Sina Anti-dsDNA Test price in Pakistan? The current cost is Rs. 3,500, and the test is available in all major cities, including:
- Islamabad
- Rawalpindi
- Lahore
- Multan
- Peshawar
- Faisalabad
- Sargodha
- Wah Cantt
- Abbottabad
You can book your test online through All Lab Tests, compare charges, and visit the nearest Ibn-e-Sina lab for sample submission.
Where to Book Anti-dsDNA Test in Pakistan
Searching for “Anti-dsDNA test near me”? You can now compare test prices, find the nearest branch, and book the Anti-dsDNA test from multiple labs nationwide through All Lab Tests.
Benefits of booking through All Lab Tests:
- Compare test charges easily
- View updated price lists for 2026
- Online appointment booking
- Fast report access
- Trusted partner labs across Pakistan
Book Your Anti-dsDNA Test at Ibn-e-Sina Clinical Laboratory
If your doctor has recommended this test, booking it is hassle-free. All Lab Tests helps you schedule your test at Ibn-e-Sina Clinical Laboratory within minutes.
- Accurate results
- Affordable price (Rs. 3,500)
- Professional staff
- Modern laboratory equipment
- Online reports
Book your Anti-dsDNA Test today and get reliable results from one of Pakistan’s most trusted diagnostic centres.