Tuberculosis (TB) remains one of the most widespread infectious diseases in Pakistan, affecting thousands of individuals every year. Early and accurate detection plays a vital role in preventing complications, protecting others, and ensuring the right treatment at the right time. One of the most trusted and advanced diagnostic options available today is the MTB DNA Detection By PCR test, and Dr. Essa Laboratory and Diagnostic Centre is among the leading diagnostic facilities providing this highly reliable test.
The MTB DNA Detection By PCR test at Dr. Essa Laboratory is performed using advanced molecular techniques that accurately identify the DNA of Mycobacterium tuberculosis, the bacteria responsible for TB. This test delivers fast and precise results compared to conventional tests, making it extremely valuable for patients, doctors, and healthcare providers.
In this detailed guide, we will cover everything you need to know: test cost, preparation, sample collection, reasons to get the test, normal ranges, report interpretation, and booking details. Whether you are searching for MTB PCR test prices, TB diagnosis options, or reliable labs in Pakistan, this article will help you make an informed decision.
What is the MTB DNA Detection By PCR Test?
The MTB DNA Detection By PCR (Polymerase Chain Reaction) test is a modern molecular diagnostic technique used to detect the genetic material (DNA) of Mycobacterium tuberculosis complex directly from a patient’s sample. Instead of waiting days for culture growth, PCR identifies TB bacteria within hours, making it one of the fastest diagnostic tools.
What the test detects:
- Presence of TB bacteria (MTB complex)
- Active TB infection
- Pulmonary and extra-pulmonary TB
- Early-stage infection before symptoms worsen
When doctors recommend this test:
- Persistent cough for more than 2-3 weeks
- Suspected TB exposure
- Chest pain, severe fatigue, or unexplained weight loss
- Non-responsive to routine antibiotics
- For patients with HIV, diabetes, or other immune disorders
- As a confirmatory test after a positive X-ray or GeneXpert
The MTB DNA PCR test is especially useful in early and difficult-to-diagnose cases, such as spinal TB, lymph node TB, and TB in children.
Why is the MTB DNA Detection By PCR Test Important?
Tuberculosis can spread silently in communities, and early detection can save lives. Traditional sputum smear tests and culture tests can take days to weeks and sometimes fail to detect low bacterial levels. This is where MTB PCR shines.
Benefits of this test include:
- High accuracy: Detects even very small amounts of TB bacteria
- Rapid results: Quicker than culture testing
- Essential for high-risk patients
- Detects both pulmonary and extra-pulmonary TB
- Critical for early treatment planning
For patients showing unexplained symptoms or for doctors managing difficult cases, PCR-based TB detection ensures the right treatment begins without delay.
When Should You Get an MTB DNA Detection By PCR Test?
Doctors may advise this test in several situations, including:
Symptoms
- Chronic cough
- Coughing up blood
- Fever and night sweats
- Weight loss
- Chest pain
- Fatigue or shortness of breath
Medical conditions
- HIV/AIDS
- Diabetes
- Chronic lung disease
- Immunosuppression (due to medications or illness)
Exposure history
- Living with a TB patient
- Workplace exposure (healthcare workers, lab staff)
- Frequent travel to high-risk areas
Diagnostic situations
- Abnormal chest X-ray
- Non-confirmatory sputum tests
- Recurring TB
- Extra-pulmonary suspected TB
If you fall into any of these categories, this test gives a clear and rapid diagnosis.
How to Prepare for the MTB DNA Detection By PCR Test?
Preparation depends on the sample required. The test is usually performed on sputum, but doctors may also request blood, tissue, pleural fluid, CSF, urine, lymph node aspirate, or other samples depending on the area of infection.
General preparation tips
- No fasting is needed.
- Drink water to stay hydrated.
- Avoid smoking before giving a sputum sample.
- If providing sputum, collect early morning samples for best accuracy.
- Inform the lab about:
- Antibiotics you are taking
- TB treatment history
- Chronic diseases
For hospitalised or special cases:
Your doctor may advise you regarding bronchoscopy samples or other fluid samples.
How the MTB DNA PCR Test is Performed at Dr Essa Laboratory
Dr Essa Laboratory adheres to international standards for sample collection, handling, and molecular testing. Their diagnostic process includes:
1. Sample collection
Depending on the suspected TB site, the sample may be:
- Sputum (most common)
- Blood
- CSF
- Pleural fluid
- Urine
- Tissue biopsies
- Lymph node aspirate
Professional technicians ensure hygienic and patient-friendly collection.
2. Sample processing
The sample is immediately processed in a controlled environment to prevent contamination.
3. DNA extraction
Bacterial DNA is isolated using advanced nucleic acid extraction systems.
4. PCR amplification
The PCR machine amplifies TB DNA if present. This process ensures high sensitivity and quick detection.
5. Report generation
Results are prepared, verified by specialists, and then shared with the patient.
Dr. Essa Laboratory is known for:
- Reliable testing
- Experienced microbiologists
- Modern molecular diagnostic machines
- Quick turnaround and accurate results
MTB DNA PCR Test Report & Normal Values
Unlike typical blood tests with numerical values, MTB PCR test report results are qualitative, meaning:
| MTB DNA PCR Result | Interpretation |
| Detected / Positive | TB DNA found – infection present |
| Not Detected / Negative | No TB DNA found – no active infection |
| Indeterminate | Repeat test recommended |
How to interpret results:
Positive result:
- Indicates TB bacteria are present in the sample
- Confirms active infection
- Doctor may prescribe anti-TB treatment
Negative result:
- MTB DNA not found
- Does NOT completely rule out TB in some cases (especially extra-pulmonary TB)
Indeterminate:
- Test needs repeat
- Could be due to low bacterial load or sample issues
Only a qualified doctor can make a final diagnosis by combining test results, symptoms, X-rays, and medical history.
Understanding Abnormal Results
If your test shows “Detected”, it means TB bacteria are present. Reasons include:
Common causes of positive results:
- Active pulmonary TB
- Extra-pulmonary TB (lymph nodes, spine, kidney, brain, etc.)
- Relapse TB
- Drug-resistant TB
- HIV-associated TB
What happens next?
Your doctor may recommend:
- Chest X-ray
- Clinical evaluation
- TB drug sensitivity testing
- Follow-up treatment plans
TB is treatable, especially when detected early.
How to Improve Lung Health Naturally
If you are being tested for TB or concerned about lung health, consider adopting these habits:
Strengthen immunity
- Vitamin C-rich foods (lemons, oranges)
- Zinc and protein intake
- Adequate sleep
Improve respiratory health
- Avoid smoking
- Practice breathing exercises
- Use a clean, ventilated living environment
Protect others
- Wear a mask if coughing
- Cover mouth while sneezing
- Avoid crowded places during illness
These cannot replace medical treatment but support general wellbeing.
MTB DNA Detection By PCR Test Cost at Dr. Essa Laboratory
The MTB DNA Detection By PCR test cost at Dr. Essa Laboratory is Rs. 9,890. This price includes professional sample handling, advanced PCR processing, and accurate reporting. The MTB PCR test at Dr. Essa Lab is trusted for its reliability, especially for patients needing rapid diagnosis.
You can easily book the MTB DNA Detection By PCR test at Dr. Essa Laboratory online and visit the nearest branch for sample collection.
Dr. Essa Laboratory MTB DNA PCR Price in Pakistan
The Dr. Essa Laboratory MTB DNA PCR Price in Pakistan is Rs. 9,890. This price may vary slightly by city or promotional offers, but All Lab Tests provides real-time updated pricing for all patients.
Booking your test online helps save time and ensures smooth sample collection.
Where to Book the MTB DNA Detection By PCR Test in Pakistan
If you are searching “MTB DNA PCR test near me”, All Lab Tests is the easiest platform to compare test costs, find the nearest Dr. Essa Laboratory branch, and book your test online.
Through All Lab Tests, you can:
- Compare MTB PCR test charges in Pakistan
- View Dr. Essa Laboratory test rates 2026
- Book tests with home sample collection (if available)
- Receive results digitally
Book Your MTB DNA Detection By PCR Test at Dr. Essa Laboratory
Take control of your health with accurate and timely testing.
You can book the MTB DNA Detection By PCR test at Dr. Essa Laboratory today through All Lab Tests and get fast, reliable, and precise results.
Enjoy:
- Convenient online booking
- Trusted laboratory network
- Quick reports
- Experienced professionals
Early diagnosis saves lives, book your test now and get the care you deserve.
