Inj Onset is a prescription anti‑emetic injection widely used in Pakistan to prevent and manage nausea and vomiting associated with chemotherapy, radiation therapy, and surgical procedures. This medication contains Ondansetron, a selective serotonin receptor antagonist known for its effectiveness in controlling severe nausea. Patients undergoing cancer treatment or those experiencing post‑operative nausea are common users of onset injection, administered under medical supervision for fast and reliable relief.
Price in Pakistan
Inj Onset is one of the preferred antiemetic options in Pakistan due to its effectiveness and clinical reliability. Prices may vary depending on the pharmacy or online provider. Always consult a licensed pharmacy or healthcare professional to check the most up-to-date price before purchasing.
Composition / Ingredients
The key active component of Inj Onset is Ondansetron, a selective 5‑HT3 receptor antagonist. Unlike vitamin injections, such as All Lab tests, Neurobion injection, which target nutritional deficiencies and nerve health, Ondansetron works specifically to block serotonin receptors that trigger nausea and vomiting. This targeted approach helps control emetic symptoms quickly and efficiently.
How It Works
Inj Onset works by blocking serotonin (5‑HT3) receptors found in both the gastrointestinal tract and central nervous system. Chemotherapy and radiation stimulate enterochromaffin cells in the intestine to release serotonin, which then activates vagal nerve pathways that signal the brain’s vomiting center.
By blocking these receptors, Ondansetron prevents nausea and vomiting before they start. In post-operative cases, a similar mechanism helps reduce nausea shortly after surgery or anesthesia. This targeted action distinguishes Inj Onset from general vitamin injections like Neurobion injection, which support nerve and vitamin health rather than controlling emesis.
Uses / Indications
Inj Onset is recommended for:
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Prevention of chemotherapy-induced nausea and vomiting in adults and pediatric patients.
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Prevention and management of post-operative nausea and vomiting following anesthesia or surgery.
It is specifically formulated for patients whose treatments trigger severe nausea, unlike vitamin injections such as vitamin B12 injection, which are intended for nutritional supplementation and nerve health support.
Dosage & Administration
Inj Onset should always be administered by a healthcare professional.
For Chemotherapy-Induced Nausea:
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Adults: 0.15 mg/kg (up to a maximum of 16 mg per dose), intravenously over 15 minutes, beginning 30 minutes before chemotherapy. Follow-up doses may be given as prescribed.
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Pediatric patients: Weight-based dosing under medical supervision.
For Postoperative Nausea and Vomiting:
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Adults: A single 4 mg dose intravenously over 2-5 minutes immediately before anesthesia induction or postoperatively if symptoms appear.
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Pediatric patients: Weight-based dosing up to 4 mg.
Always follow the doctor’s instructions to ensure safe and effective use. Improper dosing may reduce effectiveness or cause side effects.
Side Effects
Common side effects of Inj Onset include:
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Headache
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Constipation or diarrhea
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Dizziness
Less common but serious effects may include:
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Cardiac rhythm changes (QT prolongation)
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Allergic reactions such as rash or swelling
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Rare neurological effects
Because of these potential effects, monitoring by a healthcare professional is important, particularly for patients with heart or liver conditions.
Precautions & Warnings
Before using Inj Onset, consider the following:
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Hypersensitivity: Not suitable for patients with known allergies to Ondansetron.
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Drug Interactions: Can interact with medications affecting serotonin or heart rhythm.
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QT Prolongation: Avoid in patients with electrolyte imbalances or cardiac issues.
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Pregnancy & Breastfeeding: Consult a doctor before use.
These precautions are essential to ensure safe use and differentiate Inj Onset from general vitamin injections like Neurobion injection, which have a broader safety profile.
Storage & Handling
Store Inj Onset at room temperature, away from direct sunlight and heat. Keep out of reach of children. Do not use if the solution is discolored or the vial is damaged. Dispose of needles and syringes safely after use.
Comparison / Benefits vs Other Vitamin Injections
While Inj Onset is specialized for nausea control, injections like Neurobion injection or Vitamin B12 injection focus on:
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Supporting nerve health
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Addressing vitamin B deficiencies
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Boosting energy and metabolic processes
Onset injection does not provide these nutritional benefits but offers targeted relief for nausea and vomiting triggered by chemotherapy, radiation, or surgery. This makes it a focused, clinically effective option when emetic symptoms are severe.
Buy Now / How to Get Inj Onset
Inj Onset is a prescription medication in Pakistan. To obtain it safely, follow these steps:
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Consult a doctor to ensure Inj Onset is appropriate for your condition.
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Visit All Lab Tests, a trusted and licensed medical laboratory and pharmacy, to purchase the injection.
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Verify authentic packaging and confirm the dosage with your healthcare provider.
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Ensure administration by trained professionals at All Lab Tests, as proper dosing and monitoring are essential for safety and effectiveness.
By following these steps, you can access onset injection confidently through All Lab Tests and benefit from its proven antiemetic effects. Always confirm the latest availability and guidelines with your healthcare provider before use.
FAQs
1. What is Inj Onset used for?
It prevents and treats nausea and vomiting caused by chemotherapy, radiation, or surgery.
2. Is Inj Onset available without a prescription?
No, it requires a doctor’s prescription in Pakistan.
3. How is Inj Onset different from Neurobion injection?
Onset injection controls nausea, while Neurobion injection provides B vitamins to support nerve and metabolic health.
4. Can Inj Onset be self-administered?
No, it should be given only by a trained healthcare professional.
5. Are there serious drug interactions?
Yes, it can interact with serotonergic drugs or medications affecting heart rhythm. Always inform your doctor of all medications.
6. How should Inj Onset be stored?
At room temperature, away from light and heat, and out of reach of children.
7. What should I do if I experience side effects?
Contact your healthcare provider immediately for guidance. Common side effects include headache, constipation, or dizziness; serious reactions require urgent medical attention.
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