Duphaston Tablets 10mg (1 Strip = 10 Tablets)

Duphaston Tablet (Dydrogesterone) – Uses, Price, Dosage & Safety in Pakistan

Duphaston tablet is a prescription hormonal medicine widely used in Pakistan to manage female hormonal imbalance related to progesterone deficiency. It is commonly prescribed for menstrual disorders, infertility due to luteal phase deficiency, and to support pregnancy in specific conditions. Doctors rely on Duphaston because it provides progesterone support without androgenic or estrogenic effects.

Duphaston Tablet Price in Pakistan (H2)

The updated price of Duphaston tablets in Pakistan is Rs. 625 per strip (10 tablets). Prices may vary slightly depending on the pharmacy, city, and availability, so it is always recommended to check the latest price before purchasing. Platforms like All Lab tests often display updated pricing along with availability information.

Composition / Ingredients

The active ingredient in the Duphaston tablet is:

• Dydrogesterone 10 mg

Dydrogesterone is a synthetic form of progesterone that closely mimics the body’s natural hormone. Unlike some other progestins, it does not convert into estrogen or testosterone in the body. This makes it suitable for long-term hormonal support in women who need progesterone supplementation without unwanted hormonal side effects.

Duphaston does not contain vitamins or minerals; its effectiveness lies purely in its hormonal action. Because of its targeted formulation, it is commonly preferred in gynecological and fertility-related treatments.

How Duphaston Tablet Works

Progesterone is a hormone naturally produced by the ovaries after ovulation and plays a vital role in regulating the menstrual cycle and maintaining pregnancy. In some women, the body does not produce enough progesterone, leading to irregular periods, difficulty conceiving, or pregnancy complications.

Duphaston tablet works by replacing or supplementing natural progesterone in the body. Dydrogesterone binds to progesterone receptors in the uterus and helps:

• Prepare the uterine lining for implantation
• Maintain the uterine environment during early pregnancy
• Regulate menstrual cycles
• Reduce abnormal uterine bleeding

Because it closely resembles natural progesterone, it supports hormonal balance without suppressing ovulation when used correctly under medical supervision.

Uses / Indications

Doctors prescribe Duphaston tablets for several gynecological and reproductive health conditions, including:

• Female infertility due to inadequate luteal phase
• Threatened miscarriage and prevention of habitual miscarriages
• Irregular menstrual cycles
• Painful periods (dysmenorrhea)
• Dysfunctional uterine bleeding
• Secondary amenorrhea (absence of periods)
• Endometriosis (as part of hormone management)

It is especially useful for women who require progesterone support but cannot tolerate other hormonal treatments.

Dosage & Administration

The dosage of the Duphaston tablet depends on the medical condition being treated and must always be determined by a doctor.

General adult dosage (as commonly prescribed):

• 1 tablet twice daily from day 5 to day 25 of the menstrual cycle

The tablet should be swallowed with water and can be taken with or without food. Consistency in timing helps maintain stable hormone levels in the body.

Important notes:

• Do not change the dose or duration without consulting your doctor
• Children: Not applicable
• For infertility or pregnancy support, dosage schedules may differ

Always follow your gynecologist’s instructions closely for safe and effective results.

Side Effects

Like all medicines, Duphaston tablets may cause side effects, although not everyone experiences them.

Common Side Effects

• Headache or migraine
• Nausea or vomiting
• Breast tenderness or pain
• Irregular, heavy, or painful periods
• Weight gain
• Dizziness or drowsiness

Less Common or Rare Side Effects

• Skin rash, itching, or hives
• Mood changes or depression
• Fluid retention and swelling
• Anemia (low red blood cell levels)
• Hypersensitivity or allergic reactions

If any side effect becomes severe or persistent, medical advice should be sought immediately.

Precautions & Warnings

Before using the Duphaston tablet, inform your doctor about your medical history and any medicines you are taking.

When Not to Use

Do not take Duphaston if:

• You have hormone-sensitive tumors (such as meningioma)
• You experience unexplained vaginal bleeding
• You are allergic to dydrogesterone or any ingredient in the tablet

Precautions

• Contains lactose; patients with lactose intolerance should consult a doctor
• Use cautiously in patients with liver disorders
• Regular follow-ups are important during long-term use

Drug Interactions

Duphaston may interact with:

• Phenobarbital, phenytoin, carbamazepine
• Rifampicin, rifabutin
• Nevirapine, efavirenz
• Ritonavir, nelfinavir
• Insulin

Always inform your doctor about all medicines you are using to avoid reduced effectiveness or side effects.

Pregnancy & Breastfeeding

Duphaston is often prescribed during pregnancy, but it must only be used under medical supervision. Always consult a qualified healthcare provider before starting or continuing treatment.

Storage & Handling

Proper storage helps maintain the effectiveness of the Duphaston tablet:

• Store at room temperature
• Keep away from direct heat and sunlight
• Do not store in humid places
• Keep out of reach of children

Do not use the medicine after its expiry date.

Comparison / Benefits vs Other Progesterone Medicines

Compared to some other progesterone formulations, the Duphaston tablet offers several advantages:

• Does not suppress ovulation when used correctly
• Minimal androgenic or estrogenic effects
• Better tolerability in many patients
• Suitable for long-term hormonal support

These benefits make it a preferred choice for gynecologists managing fertility and menstrual disorders.

Duphaston tablet is a trusted and effective progesterone medicine used for infertility, menstrual irregularities, and pregnancy support in Pakistan. With its targeted hormonal action and favorable safety profile, it plays an important role in women’s reproductive health. Always use it under medical guidance and remember to check the updated price of Rs. 625 from reliable sources, such as All Lab tests, before purchasing.

FAQs – Duphaston Tablet

1. What is the Duphaston tablet mainly used for?
Duphaston tablet is mainly used to treat progesterone deficiency, infertility, irregular periods, and to support early pregnancy in certain conditions.

2. Can Duphaston tablets help in getting pregnant?
Yes, it is often prescribed for infertility related to luteal phase deficiency, as it helps prepare the uterus for implantation.

3. Is Duphaston tablet safe during pregnancy?
It may be prescribed during pregnancy, but only under strict medical supervision.

4. Does Duphaston tablet cause weight gain?
Some women may experience mild weight gain due to fluid retention, but this does not happen in all patients.

5. Can I take Duphaston tablet without a prescription?
No, Duphaston is a prescription medicine and should only be taken after consulting a doctor.

6. What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it is close to your next dose. Do not double the dose.

7. How long does it take for a Duphaston tablet to work?
The effect depends on the condition being treated. Some women notice improvement within one cycle, while others may require longer treatment as advised by their doctor.